| Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii | |
| Sun, Zhang-Hua; Tan, Ning-Hua; Zeng, Guang-Zhi; Zhang, Yu-Mei | |
| 2016 | |
| Source Publication | MOLECULES
 |
| Volume | 21Issue:5 |
| Abstract | Chemical investigation of the 90% acetone extract of the branches and leaves of Sabina gaussenii led to the isolation of two new cinnamyl isovalerate derivatives (1-2) and eighteen known compounds (3-20). Their structures were determined mainly by means of MS, 1D- and 2D-NMR data, and this is the first time these compounds have been reported from this plant. The biological activity test results indicated that the 90% acetone extract showed cytotoxicity against the human lung adenocarcinoma (A549) cell line (IC50 = 0.98 /- 0.1 mu g/mL), compound 6 showed cytotoxicities against human cervical carcinoma (HeLa) (IC50 = 0.4 /- 0.1 mu M) and human gastric carcinoma (BGC-823) (IC50 = 0.9 /- 0.2 mu M) cancer cell lines, and compound 19 showed cytotoxicities against HeLa (IC50 = 1.5 /- 0.4 mu M), BGC-823 (IC50 = 7.0 /- 0.8 mu M), and A549 (IC50 = 10.6 /- 1.5 mu M) cancer cell lines. |
| Keyword | Sabina Gaussenii Cinnamyl Isovalerate Cytotoxicity |
| Document Type | 期刊论文 |
| Identifier | https://ir.xtbg.ac.cn/handle/353005/9877 |
| Collection | 2012年后新成立研究组 |
| Recommended Citation GB/T 7714 | Sun, Zhang-Hua,Tan, Ning-Hua,Zeng, Guang-Zhi,et al. Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii[J]. MOLECULES,2016,21(5). |
| APA | Sun, Zhang-Hua,Tan, Ning-Hua,Zeng, Guang-Zhi,&Zhang, Yu-Mei.(2016).Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii.MOLECULES,21(5). |
| MLA | Sun, Zhang-Hua,et al."Two New Cinnamyl Isovalerate Derivatives from Sabina gaussenii".MOLECULES 21.5(2016). |
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| Two New Cinnamyl Iso（973KB） | 开放获取 | CC BY-NC-SA | View Download | |||
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