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Prenylated Isoflavonoids: Botanical Distribution, Structures, Biological Activities and Biotechnological Studies. An Update (1995-2006)
Botta, Bruno; Menendez, Pilar; Zappia, Giovanni; de Lima, Roberto Alves; Torge, Roberta; Delle Monache, Giuliano
2009
Source PublicationCURRENT MEDICINAL CHEMISTRY
ISSN0929-8673
Volume16Issue:26Pages:3414-3468
AbstractIn contrast with the parent class of flavonoids, the distribution of the isoflavonoid class in the plant kingdom is relatively limited, probably owing to the sporadic occurrence of isoflavone synthase. Isoflavonoids have been mostly found in the subfamily Fabaceae/Papilionoideae of the Leguminosae family. Isoprenoid-substituted (also called complex) isoflavonoids are expressed from a smaller number of plants, as a result of the similarly restricted distribution of prenyltransferases (PT-ase). After the reviews of Tanara & Ibrahim (1995), Boland & Donnelly (1997), the Handbook of Flavonoids by Harborne & C (Handbook of Flavonoids, 1999), and the paper by Harborne and Williams (2000) few other reports concern the distribution and the biological activity of complex isoflavonoids, except a list of isoflavonoids produced from non leguminous plants. This review deals with an update of the literature on isoprenylated isoflavonoids in the years 1995-2006 and is focused on the following highlights. 1. Natural sources of complex isoflavonoids (2000-2006) 2. Chemical structure variety: new entries (2000-2006) 3. Biological activities and a possible structure-activity relationship (1995-2006)
KeywordResistant Staphylococcus-aureus Cancer Chemopreventive Activity Cube Resin Insecticide Usaramensis Subspecies Usaramensis Cell-suspension Cultures 29 Rotenoid Constituents Pueraria-mirifica Roots Human Estrogen-receptor Erythrina-variegata Millettia-griffoniana
Subject AreaBiochemistry & Molecular Biology ; Pharmacology & Pharmacy
Indexed BySCI
Document Type期刊论文
Identifierhttps://ir.xtbg.ac.cn/handle/353005/9760
Collection文献共享
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GB/T 7714
Botta, Bruno,Menendez, Pilar,Zappia, Giovanni,et al. Prenylated Isoflavonoids: Botanical Distribution, Structures, Biological Activities and Biotechnological Studies. An Update (1995-2006)[J]. CURRENT MEDICINAL CHEMISTRY,2009,16(26):3414-3468.
APA Botta, Bruno,Menendez, Pilar,Zappia, Giovanni,de Lima, Roberto Alves,Torge, Roberta,&Delle Monache, Giuliano.(2009).Prenylated Isoflavonoids: Botanical Distribution, Structures, Biological Activities and Biotechnological Studies. An Update (1995-2006).CURRENT MEDICINAL CHEMISTRY,16(26),3414-3468.
MLA Botta, Bruno,et al."Prenylated Isoflavonoids: Botanical Distribution, Structures, Biological Activities and Biotechnological Studies. An Update (1995-2006)".CURRENT MEDICINAL CHEMISTRY 16.26(2009):3414-3468.
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