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Antioxidant and anti-tumour evaluation of compounds identified from fruit of Amomum tsaoko Crevost et Lemaire
Zhang, Tian-Tian; Lu, Chuan-Li; Jiang, Jian-Guo
2015
Source PublicationJOURNAL OF FUNCTIONAL FOODS
Volume18Issue:\Pages:423-431
AbstractThis research was aimed to isolate the active compounds with antioxidant and antitumour properties from Amomum tsaoko Crevost et Lemaire, a traditional health food in China. Ethanol (95%) extract and ethyl acetate fraction was found to have significant DPPH radical scavenging activities and cytotoxicities against cervical cancer cell Hela, hepatoma cells HepG-2 and SMMC-7721, and lung cancer cell A549. Four compounds were isolated from ethyl acetate fraction, and compounds III and IV are identified as new compounds. Compounds III and IV showed high DPPH radical scavenging activities. Compound II, III and IV exhibited good anti-tumour activity against HepG-2, SMMC-7721, Hela and A549 cell lines. Compound! showed a strong anti-tumour activity only against Hela cell lines. Compounds III and IV were concluded to be the active compositions responsible for potent antioxidant and anti-tumour properties of A. tsaoko, whose molecular mechanism and pathways of inhibiting tumour cell need to be further studied.
KeywordAmomum Tsaoko Crevost Et Lemaire Antioxidant Anti-tumour Diarylheptanoids Identification
Document Type期刊论文
Identifierhttps://ir.xtbg.ac.cn/handle/353005/9667
Collection2012年后新成立研究组
Recommended Citation
GB/T 7714
Zhang, Tian-Tian,Lu, Chuan-Li,Jiang, Jian-Guo. Antioxidant and anti-tumour evaluation of compounds identified from fruit of Amomum tsaoko Crevost et Lemaire[J]. JOURNAL OF FUNCTIONAL FOODS,2015,18(\):423-431.
APA Zhang, Tian-Tian,Lu, Chuan-Li,&Jiang, Jian-Guo.(2015).Antioxidant and anti-tumour evaluation of compounds identified from fruit of Amomum tsaoko Crevost et Lemaire.JOURNAL OF FUNCTIONAL FOODS,18(\),423-431.
MLA Zhang, Tian-Tian,et al."Antioxidant and anti-tumour evaluation of compounds identified from fruit of Amomum tsaoko Crevost et Lemaire".JOURNAL OF FUNCTIONAL FOODS 18.\(2015):423-431.
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