Institutional Repository of Xishuangbanna Tropical Botanical Garden
| Evaluation of the Cytotoxic Activity of Some Brazilian Medicinal Plants | |
| Ribeiro, S. S. | |
| 2012 | |
| Source Publication | Planta Medica
 |
| ISSN | 0032-0943 |
| Volume | 78Issue:14Pages:1601-1606 |
| Abstract | Plants are promising sources of new bioactive compounds. The aim of this study was to investigate the cytotoxic potential of nine plants found in Brazil. The species studied were: Annona pickelii Diels (Annonaceae), Annona salzmannii A. DC. (Annonaceae), Guatteria blepharophylla Mart. (Annonaceae), Guatteria hispida (R. E. Fr.) Erkens & Maas (Annonaceae), Hancornia speciosa Gomes (Apocynaceae), Jatropha curcas L. (Euphorbiaceae), Kielmeyera rugosa Choisy (Clusiaceae), Lippia gracilis Schauer (Verbenaceae), and Hyptis calida Mart. Ex Benth (Lamiaceae). Different types of extractions from several parts of plants resulted in 43 extracts. Their cytotoxicity was tested against HCT-8 (colon carcinoma), MDA-MB-435 (melanoma), SF-295 (glioblastoma), and HL-60 (promielocitic leukemia) human tumor cell lines, using the thiazolyl blue test (MTT) assay. The active extracts were those obtained from G. blepharophylla, G. hispida, J. curcas, K. rugosa, and L. gracilis. In addition, seven compounds isolated from the active extracts were tested; among them, beta-pinene found in G. hispida and one coumarin isolated from K. rugora showed weak cytotoxic activity. In summary, this manuscript contributes to the understanding of the potentialities of Brazilian plants as sources of new anticancer drugs. |
| Document Type | 期刊论文 |
| Identifier | https://ir.xtbg.ac.cn/handle/353005/8047 |
| Collection | 热带植物资源可持续利用重点实验室特色文献_小桐子相关文献 |
| Recommended Citation GB/T 7714 | Ribeiro, S. S.. Evaluation of the Cytotoxic Activity of Some Brazilian Medicinal Plants[J]. Planta Medica,2012,78(14):1601-1606. |
| APA | Ribeiro, S. S..(2012).Evaluation of the Cytotoxic Activity of Some Brazilian Medicinal Plants.Planta Medica,78(14),1601-1606. |
| MLA | Ribeiro, S. S.."Evaluation of the Cytotoxic Activity of Some Brazilian Medicinal Plants".Planta Medica 78.14(2012):1601-1606. |
| Files in This Item: | Download All | |||||
| File Name/Size | DocType | Version | Access | License | ||
| Evaluation of the Cy（115KB） | 开放获取 | CC BY-NC-SA | View Download | |||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment