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Genome-wide association studies for common diseases and complex traits
Joel N. Hirschhorn; Mark J. Daly
2005
Source PublicationNature Reviews Genetics
Volume6Issue:xPages:95-108
AbstractGenetic factors strongly affect susceptibility to common diseases and also influence disease-related quantitative traits. Identifying the relevant genes has been difficult, in part because each causal gene only makes a small contribution to overall heritability. Genetic association studies offer a potentially powerful approach for mapping causal genes with modest effects, but are limited because only a small number of genes can be studied at a time. Genome-wide association studies will soon become possible, and could open new frontiers in our understanding and treatment of disease. However, the execution and analysis of such studies will require great care.
Document Type期刊论文
Identifierhttps://ir.xtbg.ac.cn/handle/353005/4692
Collection文献共享
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GB/T 7714
Joel N. Hirschhorn,Mark J. Daly. Genome-wide association studies for common diseases and complex traits[J]. Nature Reviews Genetics,2005,6(x):95-108.
APA Joel N. Hirschhorn,&Mark J. Daly.(2005).Genome-wide association studies for common diseases and complex traits.Nature Reviews Genetics,6(x),95-108.
MLA Joel N. Hirschhorn,et al."Genome-wide association studies for common diseases and complex traits".Nature Reviews Genetics 6.x(2005):95-108.
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