Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity

doi:10.1016/S1875-5364(21)60112-7

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	Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity
	Liu Yu ; You Yun-Xia ; Rao Li ; He Qian ; Su Yu ; Fan Yue ; Li Yi-Zhou ; Xu You-Kai; Zhang Chuan-Rui
	2022
Source Publication	CHINESE JOURNAL OF NATURAL MEDICINES
ISSN	2095-6975
Volume	20 Issue:2 Pages:139-147
Abstract	Fourteen new geranyl phenyl ethers (1-14) along with three known compounds (15-17) were isolated from Illicium micranthum, and their structures were elucidated by comprehensive spectroscopic methods. Illimicranins A-H (1-8) were characterized as geranyl vanillin ethers, while 9 and 10 were dimethyl acetal derivatives. Illimicranins I and J (11 and 12) were rare geranyl isoeugenol ethers. Illimicranins K and L (13 and 14) represented the first example of geranyl guaiacylacetone ether and geranyl zinger one ether, respectively. Compounds 1, 2 and 15 exhibited anti-HBV (hepatitis B virus) activity against HBsAg (hepatitis B surface antigen) and HBeAg (hepatitis B e antigen) secretion, and HBV DNA replication.
Keyword	Illicium micranthum Geranyl phenyl ethers Spectroscopic data Anti-HBV activity
Subject Area	Integrative & Complementary Medicine ; Pharmacology & Pharmacy
DOI	10.1016/S1875-5364(21)60112-7
Indexed By	SCI
Language	英语
WOS ID	WOS:000768386200006
Citation statistics
Document Type	期刊论文
Identifier	https://ir.xtbg.ac.cn/handle/353005/13004
Collection	民族植物学研究组
Affiliation	1.[Liu Yu 2.You Yun-Xia 3.Rao Li 4.He Qian 5.Su Yu 6.Fan Yue 7.Li Yi-Zhou 8.Chongqing Univ, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing 401331, Peoples R China 9.Chongqing Univ, Sch Pharmaceut Sci, Chem Biol Res Ctr, Chongqing 401331, Peoples R China 10.Chinese Acad Sci, Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China 11.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China
Recommended Citation GB/T 7714	Liu Yu,You Yun-Xia,Rao Li,et al. Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity[J]. CHINESE JOURNAL OF NATURAL MEDICINES,2022,20(2):139-147.
APA	Liu Yu.,You Yun-Xia.,Rao Li.,He Qian.,Su Yu.,...&Zhang Chuan-Rui.(2022).Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity.CHINESE JOURNAL OF NATURAL MEDICINES,20(2),139-147.
MLA	Liu Yu,et al."Geranyl phenyl ethers from Illicium micranthum and their anti-HBV activity".CHINESE JOURNAL OF NATURAL MEDICINES 20.2(2022):139-147.

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