| A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata | |
Liu, Xin; Tang, Gui-Hua; Weng, Han-Zhuang; Zhang, Jun-Sheng; Xu, You-Kai ; Yin, Sheng4
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| 2018 | |
| Source Publication | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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| ISSN | 1028-6020 |
| Volume | 20Issue:12Pages:1123-1128 |
| Abstract | Five selaginellin derivatives (1 and 3-6) including a new one, selaginellin T (1), and a new triarylbenzophenone analog, selagibenzophenone A (2), were isolated from the whole plants of Selaginella pulvinata. Their structures were determined by 1D- and 2D-NMR and HR-ESI-MS data. Selagibenzophenone A (2) is the first example of naturally occurring triarylbenzophenone. The results of the phosphodiesterase-4 (PDE4) inhibitory screening assays showed that compounds 1-6 exhibited potent activities with the IC50 values in the range of 1.04-9.35 mu M. [GRAPHICS] . |
| Keyword | Phosphodiesterase-4 Inhibitors Natural Pigment Tamariscina |
| Subject Area | Plant Sciences ; Chemistry ; Pharmacology & Pharmacy |
| DOI | 10.1080/10286020.2017.1378646 |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000459882800004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | https://ir.xtbg.ac.cn/handle/353005/11247 |
| Collection | 民族植物学研究组 |
| Affiliation | 1.[Liu, Xin 2.Tang, Gui-Hua 3.Weng, Han-Zhuang 4.Zhang, Jun-Sheng 5.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Guangdong, Peoples R China 6.Chinese Acad Sci, Key Lab Trop Plant Resource & Sustainable Use, Xishuangbanna Trop Bot Garden, Menglun 666303, Peoples R China |
| Recommended Citation GB/T 7714 | Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,et al. A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2018,20(12):1123-1128. |
| APA | Liu, Xin,Tang, Gui-Hua,Weng, Han-Zhuang,Zhang, Jun-Sheng,Xu, You-Kai,&Yin, Sheng.(2018).A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,20(12),1123-1128. |
| MLA | Liu, Xin,et al."A new selaginellin derivative and a new triarylbenzophenone analog from the whole plant of Selaginella pulvinata".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 20.12(2018):1123-1128. |
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| A new selaginellin d（1039KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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