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Maximumins A-D, Rearranged Labdane-Type Diterpenoids with Four Different Carbon Skeletons from Amomum maximum
Ji, Kai-Long; Fan, Yao-Yue; Ge, Zhan-Peng; Sheng, Li; Xu, You-Kai; Gang, Li-She; Li, Jing-Ya; Yue, Jian-Min
2019
Source PublicationJOURNAL OF ORGANIC CHEMISTRY
ISSN0022-3263
Volume84Issue:1Pages:282-288
Abstract

Four highly rearranged labdane-type diterpenoids, maximumins A-D (1-4) possessing different new carbon skeletons, together with a biosynthetically related known analog 5 were isolated from Amomum maximum. The structures of new compounds with absolute configurations were characterized by spectroscopic and computational approaches. The plausible biogenetic pathways for 1-4 were proposed. These compounds showed moderate to weak activities against nuclear factor kappa B (NF-kappa B).

KeywordNf-kappa-b Inhibitor
Subject AreaChemistry
DOI10.1021/acs.joc.8b02665
Indexed BySCI
Language英语
WOS IDWOS:000455286100023
Citation statistics
Document Type期刊论文
Identifierhttps://ir.xtbg.ac.cn/handle/353005/11222
Collection民族植物学研究组
Affiliation1.[Ji, Kai-Long
2.Fan, Yao-Yue
3.Ge, Zhan-Peng
4.Sheng, Li
5.Li, Jing-Ya
6.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd,Zhangjiang Hitech Pk, Shanghai 201203, Peoples R China
7.Chinese Acad Sci, Xishuangbanna Trop Bot Garden, Key Lab Trop Plant Resources & Sustainable Use, Menglun 666303, Peoples R China
8.Zhejiang Univ, Coll Pharmaceut Sci, Inst Modern Chinese Med, Hangzhou 310058, Zhejiang, Peoples R China
Recommended Citation
GB/T 7714
Ji, Kai-Long,Fan, Yao-Yue,Ge, Zhan-Peng,et al. Maximumins A-D, Rearranged Labdane-Type Diterpenoids with Four Different Carbon Skeletons from Amomum maximum[J]. JOURNAL OF ORGANIC CHEMISTRY,2019,84(1):282-288.
APA Ji, Kai-Long.,Fan, Yao-Yue.,Ge, Zhan-Peng.,Sheng, Li.,Xu, You-Kai.,...&Yue, Jian-Min.(2019).Maximumins A-D, Rearranged Labdane-Type Diterpenoids with Four Different Carbon Skeletons from Amomum maximum.JOURNAL OF ORGANIC CHEMISTRY,84(1),282-288.
MLA Ji, Kai-Long,et al."Maximumins A-D, Rearranged Labdane-Type Diterpenoids with Four Different Carbon Skeletons from Amomum maximum".JOURNAL OF ORGANIC CHEMISTRY 84.1(2019):282-288.
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