Chinese | English
XTBG OpenIR  > 文献共享
Signal integration in the endoplasmic reticulum unfolded protein response
Ron, D; Walter, P
2007
Source PublicationNATURE REVIEWS MOLECULAR CELL BIOLOGY
ISSN1471-0072
Volume8Issue:7Pages:519-529
AbstractThe endoplasmic reticulum ( ER) responds to the accumulation of unfolded proteins in its lumen (ER stress) by activating intracellular signal transduction pathways-cumulatively called the unfolded protein response (UPR). Together, at least three mechanistically distinct arms of the UPR regulate the expression of numerous genes that function within the secretory pathway but also affect broad aspects of cell fate and the metabolism of proteins, amino acids and lipids. The arms of the UPR are integrated to provide a response that remodels the secretory apparatus and aligns cellular physiology to the demands imposed by ER stress.
KeywordMessenger-rna Translation Plasma-cell Differentiation Induced Gene-expression Er Stress Transcription Factor Transmembrane Protein Glucose-homeostasis Hypoxic Stress Proapoptotic Bax Mammalian-cells
Indexed ByWOS:000247463500012
Language英语
Document Type期刊论文
Identifierhttps://ir.xtbg.ac.cn/handle/353005/10250
Collection文献共享
Recommended Citation
GB/T 7714		 Ron, D,Walter, P. Signal integration in the endoplasmic reticulum unfolded protein response[J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY,2007,8(7):519-529.
APA Ron, D,&Walter, P.(2007).Signal integration in the endoplasmic reticulum unfolded protein response.NATURE REVIEWS MOLECULAR CELL BIOLOGY,8(7),519-529.
MLA Ron, D,et al."Signal integration in the endoplasmic reticulum unfolded protein response".NATURE REVIEWS MOLECULAR CELL BIOLOGY 8.7(2007):519-529.
Files in This Item: Download All
File Name/Size DocType Version Access License
Signal integration i（1506KB） 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Ron, D]'s Articles
[Walter, P]'s Articles
Baidu academic
Similar articles in Baidu academic
[Ron, D]'s Articles
[Walter, P]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Ron, D]'s Articles
[Walter, P]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: Signal integration in the endoplasmic reticulum unfolded protein response.pdf
Format: Adobe PDF
This file does not support browsing at this time
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.