| Neuroprotective and Anti-Inflammatory Effects of Diphenylheptanes from the Fruits of Amomum tsaoko, a Chinese Spice | |
| Zhang, Tian-Tian; Lu, Chuan-Li; Jiang, Jian-Guo | |
| 2016 | |
| Source Publication | PLANT FOODS FOR HUMAN NUTRITION
 |
| Volume | 71Issue:4Pages:450-453 |
| Abstract | Two novel diphenylheptanes, 2,3- dihydro-2 - (4' - hydroxy-phenylethyl) - 6 - [(3aEuro(3),4aEuro(3) - dihydroxy-5" - methoxy) phenyl] -4 - pyrone (CG-A) and 4 - dihydro-2 - (4' - hydroxy-phenylmethyl) -6 - [(3",4aEuro(3) - dihydroxy-5aEuro(3) - methoxyphenyl) methylene]-pyran-3, 5 - dione (CG-B), were isolated from the dried fruits of Amomum tsaoko, a commercially important spice. This study was designed to investigate their protective effects against H2O2-induced nerve injury, using PC-12 cells to determine the cell cytotoxicity and cell viability. The inhibitory effect on (nitric oxide) NO production was also determined in (lipopolysaccharide) LPS-stimulated macrophage RAW 264.7 cells. The results showed that CG-A and CG-B displayed significant neuroprotective effect and exhibited anti-inflammatory activity in a dose-dependent manner. These findings suggest that CG-A and CG-B are very important nutritional ingredients responsible for the neuroprotective and anti-inflammatory health benefits of A. tsaoko. |
| Keyword | Amomum Tsaoko Diphenylheptanes Neuroprotective Effect Anti-inflammatory |
| Document Type | 期刊论文 |
| Identifier | https://ir.xtbg.ac.cn/handle/353005/10169 |
| Collection | 园林园艺部 |
| Recommended Citation GB/T 7714 | Zhang, Tian-Tian,Lu, Chuan-Li,Jiang, Jian-Guo. Neuroprotective and Anti-Inflammatory Effects of Diphenylheptanes from the Fruits of Amomum tsaoko, a Chinese Spice[J]. PLANT FOODS FOR HUMAN NUTRITION,2016,71(4):450-453. |
| APA | Zhang, Tian-Tian,Lu, Chuan-Li,&Jiang, Jian-Guo.(2016).Neuroprotective and Anti-Inflammatory Effects of Diphenylheptanes from the Fruits of Amomum tsaoko, a Chinese Spice.PLANT FOODS FOR HUMAN NUTRITION,71(4),450-453. |
| MLA | Zhang, Tian-Tian,et al."Neuroprotective and Anti-Inflammatory Effects of Diphenylheptanes from the Fruits of Amomum tsaoko, a Chinese Spice".PLANT FOODS FOR HUMAN NUTRITION 71.4(2016):450-453. |
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